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Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?

Tomljenovic L, Shaw CA. Do aluminum vaccine adjuvants contribute to the rising prevalence of autism? J Inorg Biochem. 2011 Nov;105(11):1489-99. doi: 10.1016/j.jinorgbio.2011.08.008. Epub 2011 Aug 23. PMID: 22099159.

Our results show that: (i) children from countries with the highest ASD prevalence appear to have the highest exposure to Al from vaccines; (ii) the increase in exposure to Al adjuvants significantly correlates with the increase in ASD prevalence in the United States observed over the last two decades

Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure

Seneff, S.; Davidson, R.M.; Liu, J. Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure. Entropy 2012, 14, 2227-2253.

In this paper, we have presented some analyses of the VAERS database which strongly suggest that the aluminum in vaccines is toxic to vulnerable children. While we have not shown that aluminum is directly causative in autism, the compelling evidence available from the literature on the toxicity of aluminum, combined with the evidence we present for severe adverse reactions occurring much more frequently following administration of aluminum-containing vaccines as compared to non-aluminum-containing vaccines, suggests that neuronal damage due to aluminum penetration into the nervous system may be a significant factor in autism.

Experimental Epilepsy in the Monkey Following Multiple Intracerebral Injections of Alumina Cream

Joseph G. Chusid, Lenore M. Kopeloff, Ph.D. and Nicholas Kopeloff, Ph.D. The Bulletin, 1953.

Aluminum caused tics and grand mal seizures in monkeys.

Macrophagic myofasciitis lesions assess long-term persistence of vaccine derived aluminum hydroxide in muscle

R.K. Gherardi, M. Coquet, P. Cherin, L. Belec, P. Moretto, P.A. Dreyfus. Brain, 2001, 124, 1821-1831.

French scientists tie aluminum adjuvant in vaccine to macrophagic myofasciitis.

Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction

Maryline Couette, Marie-Françoise Boisse, Patrick Maison, Pierre Brugieres, Pierre Cesaro, Xavier Chevalier, Romain K. Gherardi, Anne-Catherine Bachoud-Levi, François-Jérôme Authier. Journal of Inorganic Biochemistry, 2009.

French scientists report aluminum from vaccines causes chronic cognitive dysfunction.

Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity

Shaw C, Tomljenovic L. Immunologic Research. 2013;56:304–316.

Canadian researchers: aluminum in vaccines can cause both autoimmunity and neurological damage.

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) 2013: Unveiling the pathogenic, clinical and diagnostic aspects

Perricone C, Colafrancesco S, Mazor RD, Soriano A, Agmon-Levin N, Shoenfeld Y. Journal of Autoimmunity. 2013;47:1-16.

Israeli and Italian researchers demonstrate that exposure to aluminum in vaccines can lead to autoimmune and brain dysfunction.

Aluminum exposure and toxicity in neonates: a practical guide to halt aluminum overload in the prenatal and perinatal periods.

Fanni D, et al. World Journal of Pediatrics, 2014 May; 10(2):101-7.

Newborns have been overexposed to aluminum.

Neuroprotective effect of Allium cepa L. in aluminium chloride induced neurotoxicity

Tanveer Singh and Rajesh Kumar Goel. NeuroToxicology, 49 (2015) 1–7.

Chronic aluminium administration resulted in significant motor incoordination and memory deficits, which were also endorsed biochemically as there was increased oxidative stress as well as elevated aluminium levels in the brain.

Assessment of hair aluminum, lead, and mercury in a sample of autistic Egyptian children: Environmental risk factors of heavy metals in autism

El Baz Mohamed F, Zaky EA, Bassuoni EI-Sayed A, et al. Behavioural Neurology. 2015, Article ID 545674.

Autistic children accumulate metals at a much higher level than children who do not have a diagnosis of autism.

On vaccine’s adjuvants and autoimmunity: Current evidence and future perspectives

Pellegrino P, Clementi E, Radice S. Autoimmunity Reviews. 2015;14(10):880-888.

The specific mechanism of action of each vaccine adjuvant may have different effects on the course of autoimmune conditions resulting from vaccination

Aluminum in Childhood Vaccines Is Unsafe

Neil Z. Miller. Journal of American Physicians and Surgeons, Winter 2016.

Aluminum in vaccines is highly neurotoxic and exposure levels given to infants have dramatically increased.

Behavioral abnormalities in female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil

Inbar R, Weiss R, Tomljenovic L, Arango M-T, Deri Y, Shaw CA, Chapman J, Blank M, Shoenfeld Y. Immunologic Research. 2017;65(1):136-149.

Israeli, Canadian and Colombian scientists show that the Gardasil vaccine triggers brain inflammation and autoimmunity in mice.

Combined subchronic toxicity of aluminum (III), titanium (IV) and silicon (IV) oxide nanoparticles and its alleviation with a complex of bioprotectors

IA Minigalieva, BA Katsnelson, LI Privalova, et al. International Journal of Molecular Sciences, March 2018;19(3):837.

Aluminum nanoparticles are toxic on their own and in combination with other metal nanoparticles.

Synergism in aluminum and mercury neurotoxicity

Peter N Alexandrov,1 Aileen I Pogue,2 and Walter J Lukiw

Aluminum and mercury sulfates may contribute to neurodegeneration and progressive age-related functional decline such as Alzheimer’s disease.

Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum

James Lyons-Weiler 1, Robert Ricketson 2

The levels of aluminum present in individual vaccines and in the modern vaccine schedule as a whole are problematically high.

Aluminium in brain tissue in multiple sclerosis

Matthew Mold,1 Agata Chmielecka,2 Maria Raquel Ramirez Rodriguez,1 Femia Thom,2 Caroline Linhart,3 Andrew King,4 and Christopher Exley1,*

The first-ever measurements of aluminum in the brain tissue of donors with multiple sclerosis detected pathologically significant levels of aluminum in every single individual.

Immunoexcitotoxicity as the central mechanism of etiopathology and treatment of autism spectrum disorders: a possible role of fluoride and aluminum

Strunecka A, Blaylock RL, Patocka J, Strunecky O. Surgical Neurology International. 2018;9:74.

Fluoride and aluminum, alone or in combination, can produce the condition of “immunoexcitotoxicity” that leads to the pathological changes seen in autism.

Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action

Emma Shardlow, Matthew Mold & Christopher Exley

Aluminum adjuvants in vaccines produce toxic effects ranging from benign to fatal, depending on the physicochemical properties of the adjuvant and the physiological response of the vaccine recipient.

Aluminium toxicosis: a review of toxic actions and effects

Ikechukwu Onyebuchi Igbokwe, Ephraim Igwenagu, Nanacha Afifi Igbokwe. Interdiscip Toxicol. 2019; Vol. 12(2): 45–70. doi: 10.2478/intox-2019-0007

With the preliminary literature search starting in 2013 and looking backwards in time, research publications revealed a myriad of toxic actions of Aluminum causing pathological conditions.

Acute exposure and chronic retention of aluminum in three vaccine schedules and effects of genetic and environmental variation

Journal of Trace Elements in Medicine and Biology

Among the three schedules presented here, the CDC schedule exceeds the recommended dose limit for an infant (inferred from FDA adult “safe” levels) as a result of the simultaneous administration of multiple ACVs and insufficient spacing of ACVs.

Imaging of aluminium and amyloid β in neurodegenerative disease

Christopher Exley∗ and Matthew J. Mold

We suggest that complementary aluminium-specific fluorescence microscopy may reveal important information about the putative toxicity of aluminium in neurodegenerative and neurodevelopmental disorders.

Association Between Aluminum Exposure From Vaccines Before Age 24 Months and Persistent Asthma at Age 24 to 59 Months

Academic Pediatrics

In a large observational study, a positive association was found between vaccine-related aluminum exposure and persistent asthma. While recognizing the small effect sizes identified and the potential for residual confounding, additional investigation of this hypothesis appears warranted.

Aluminum and Alzheimer's Disease: After a Century of Controversy, Is there a Plausible Link?

IOS Press

The hypothesis that Al significantly contributes to AD is built upon very solid experimental evidence and should not be dismissed. Immediate steps should be taken to lessen human exposure to Al, which may be the single most aggravating and avoidable factor related to AD.

Aluminum adjuvant linked to gulf war illness induces motor neuron death in mice


The findings suggest a possible role for the aluminum adjuvant in some neurological features associated with GWI and possibly an additional role for the combination of adjuvants.

Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes

Journal of Inorganic Biochemistry

Repetitive administration of aluminium to neonatal mice in amounts comparable to those to children receive via routine vaccinations significantly increases anxiety and reduces exploratory behaviour and locomotor activities. The neurodisruptive effects of aluminium are long-lasting and persist for 6 months following injection.


Jefferey Jaxen

A new study published in the Journal of Trace Elements in Medicine and Biology concluded the U.S. Centers for Disease Control and Prevention’s (CDC) vaccine schedule was 15.9 times over the recommended safe level of aluminum when researchers adjusted for body weight.

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